UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                   WASHINGTON, D.C. 20549
                              
                          FORM 8-K

                       CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange
Act of 1934


                        APRIL 30, 1998
                        --------------
              (Date of earliest event reported)
                              
                              
                              
         LABORATORY CORPORATION OF AMERICA HOLDINGS
         ------------------------------------------
   (Exact name of registrant as specified in its charter)
                              


   DELAWARE                1-11353            13-3757370
   --------                -------            ----------
(State or other          (Commission        (IRS Employer
jurisdiction or          File Number)        Identification
organization)                                Number)


                              
  358 SOUTH MAIN STREET, BURLINGTON, NORTH CAROLINA  27215
  --------------------------------------------------------
          (Address of principal executive offices)
                              
                              
                              
                        336-229-1127
                        ------------
      (Registrant's telephone number, including area code)




ITEM 5. OTHER EVENTS

On April 30, 1998, Laboratory Corporation of America Holdings
(the "Company") issued a press release dated as of such date
announcing operating results of the Company for the quarter
ended March 31, 1998, as well as certain other information.
The press release is attached as an exhibit hereto and the text
thereof is incorporated in its entirety herein by reference.


ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL
         INFORMATION AND EXHIBITS

  (c) Exhibit
                              
      20  Press release of the Company dated April 30, 1998.



                         SIGNATURES
                              
      Pursuant to the requirements of the Securities and
Exchange Act of 1934, the registrant has duly caused this
report to be signed on its behalf by the undersigned hereunto
duly authorized.

               LABORATORY CORPORATION OF AMERICA HOLDINGS
               ------------------------------------------
                             (Registrant)



                    By:/s/ WESLEY R.ELINGBURG
                       -----------------------
                           Wesley R. Elingburg
                           Executive Vice President,
                           Chief Financial Officer and
                           Treasurer (Principal Financial
                           Officer and Principal
                           Accounting Officer)



Date: May 7, 1998




FOR IMMEDIATE RELEASE
                                   PAMELA SHERRY - INVESTOR RELATIONS CONTACT
                                   336-584-5171, EXT. 4855

                                   LABCORP SHAREHOLDER DIRECT 800-LAB-0401


 LABORATORY CORPORATION OF AMERICA-REGISTERED TRADEMARK- REPORTS
                      FIRST QUARTER RESULTS

                                
                                
BURLINGTON,  NC,  APRIL  30,  1998 - Laboratory  Corporation  of
America-Registered   Trademark-   Holdings   (LabCorp-Registered
Trademark-) (NYSE: 1LH) today announced results for the  quarter
ended March 31, 1998.

Net  sales  for the first quarter were $373.0 million, operating
income $29.4 million, and net income $9.3 million.  The loss per
common  share  on  a  basic and diluted basis  (after  deducting
preferred  stock dividends) was $0.01.  This compares  with  net
sales of $391.5 million, operating income of $27.8 million,  net
income  of  $2.4  million, and basic and  diluted  earnings  per
common share of $0.02 for the same period in 1997.

The  revenue decline is the result of a 4.6% reduction in volume
compared  to  the first quarter of 1997.  This is a decrease  in
the rate of decline noted in each of the last three quarters  in
1997, when declines approximated 7% versus comparable periods in
1996.   The volume decline is attributable to LabCorp's  program
of  shedding  unprofitable  business,  as  well  as  changes  in
physicians'  ordering  patterns caused  by  new  government  and
private   reimbursement  policies,  and  hospitals  aggressively
competing  in the outpatient testing market.  Despite a  January
1,  1998 decrease in the Medicare fee schedule, price during the
quarter remained level with the comparable period in 1997.

Earnings  before interest, taxes, depreciation, and amortization
(EBITDA),  considered by LabCorp to be the best  measurement  of
its  performance,  was $50.2 million for the  first  quarter  of
1998,  or 13.5% of net sales, versus $49.2 million, or 12.6%  of
net  sales,  for  the  comparable period  in  1997.   Furthering
LabCorp's  trend in operating expense reduction,  first  quarter
1998  operating  expenses declined by 5.5%,  or  $20.1  million,
compared to the same period in 1997.

"We  are  pleased with our first quarter results, which were  in
line with our expectations," said Thomas P. Mac Mahon, President
and  Chief Executive Officer. "Our days sales outstanding  (DSO)
remained  at the same level as reported for year-end 1997.   Our
operating  cash flow for the quarter was $27.9  million.   As  a
result,  we  were able to pay-down $30.0 million in debt  during
the  quarter.   We remain committed to lowering DSO,  increasing
cash  collections,  reducing costs, and improving  price  as  we
proceed  with  enhancements  to  our  billing  system  and   the
implementation of our new strategic plan to strengthen our  core
business and create new revenue-generating opportunities."

On  April  28, 1998, LabCorp announced an exclusive  partnership
with  Virco  to  offer  important new tests  that  will  provide
physicians   treating  HIV-infected  patients  drug   resistance
information.    These   tests  will  provide   physicians   with
information  about which components of anti-HIV  drug  cocktails
for  individual patients are likely to be effective,  and  which
drugs  are  not.   LabCorp  is  planning  to  use  Virco's   new
phenotyping  technology  to enhance the  analysis  of  genotypic
testing,  which  identifies genetic mutations that  can  signify
drug  resistance.   LabCorp will have exclusive  access  to  the
first  HIV  resistance database that directly relates  genotypic
analysis to phenotypic interpretation.  Developed by Virco,  the
Company believes the database provides the most useful guide for
AIDS-treating physicians to date.

During  the  quarter,  LabCorp completed the  acquisition  of  a
laboratory in St. Petersburg, Florida representing approximately
$3  million in annual revenues.  In March, consistent  with  its
strategic plan for growth, LabCorp completed the divestiture  of
its  veterinary business in an asset sale to Antech Diagnostics,
a  subsidiary of Veterinary Centers of America, Inc.,  resulting
in  a gain on the divestiture of $2.0 million.  And on April 22,
the Company also entered into an agreement to acquire certain of
the  assets  of  Medlab,  Inc.  Based in  Wilmington,  Delaware,
Medlab,  Inc.  is  the  largest provider of clinical  laboratory
testing  services in Delaware with annual revenues  in  1997  of
approximately $20 million.

The  Company  noted  that  each  of  the  above  forward-looking
statements  was  subject to change based  on  various  important
factors,  including without limitation, competitive  actions  in
the  marketplace and adverse actions of governmental  and  other
third-party  payors.  Further information on  potential  factors
that could affect the Company's financial results is included in
the Company's Form 10-K for the year ended December 31, 1997.

Laboratory Corporation of America-Registered Trademark- Holdings
(LabCorp-Registered   Trademark-)   is   a   national   clinical
laboratory organization with annual revenues of $1.5 billion  in
1997.    The   Company   operates  primary  testing   facilities
nationally, offering more than 1,700 different clinical  assays,
from  routine blood analyses to more sophisticated technologies.
LabCorp  performs diagnostic tests for physicians,  managed-care
organizations,  hospitals, clinics, long-term  care  facilities,
industrial companies and other clinical laboratories.
                                
                                
                         - End of Text -
                                
                       - Table to Follow -
                                
                                



                                
           LABORATORY CORPORATION OF AMERICA HOLDINGS
                Summarized Financial Information
          (Dollars in millions, except per share data)
                                
                                        (Unaudited)
                                     Three Months Ended
                                          March 31,
                                   ----------------------
                                     1998          1997

                                                     
Net sales                          $ 373.0       $ 391.5
                                   =======       =======

Operating income                      29.4          27.8
                                   =======       =======

Earnings before income taxes          18.8           5.9

Provision for income taxes             9.5           3.5
                                   -------       -------

Net earnings                       $   9.3       $   2.4

Less preferred stock dividends
 and accretion of manditorily
 redeemable preferred stock           11.1            --
                                   -------       -------

Net gain (loss) attributable to
 common shareholders               $  (1.8)      $   2.4
                                   =======       =======

Basic and diluted earnings
 (loss) per share (1)              $ (0.01)      $  0.02
                                   =======       =======


(1) Earnings (loss) per common share are based on the weighted
average number of shares outstanding during the three-month periods
ended March 31, 1998 and March 31, 1997 of 124,397,665 shares and
122,935,080 shares, respectively