SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                            -----------------------


                                  SCHEDULE 13D
                                 (Rule 13d-101)

            INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULE 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO
                                 RULE 13d-2(a)

                               (Amendment No. 2)

                   LABORATORY CORPORATION OF AMERICA HOLDINGS
- --------------------------------------------------------------------------------
                                (Name of Issuer)

                         COMMON STOCK, $0.10 PAR VALUE
- --------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                  50540R 40 9
- --------------------------------------------------------------------------------
                                 (CUSIP Number)

                             Peter R. Douglas, Esq.
                             Davis Polk & Wardwell
                              450 Lexington Avenue
                               New York, NY 10017
                            Tel. No.: (212) 450-4000
- --------------------------------------------------------------------------------
                 (Name, Address and Telephone Number of Person
               Authorized to Receive Notices and Communications)

                                June 26, 27, 29, 2000
- --------------------------------------------------------------------------------
            (Date of Event which Requires Filing of This Statement)

     If the filing person has previously filed a statement on Schedule 13G to
report the acquisition which is the subject of this Schedule 13D, and is filing
this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the
following box [ ].

     The information required on the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).

                      (Continued on the following pages)

                              (Page 1 of 9 Pages)

Schedule 13D - -------------------------------------------------------------------------------- - --------------------- ----------------------- CUSIP No. 5054OR 40 9 13D Page 2 of 9 Pages - --------------------- ----------------------- 1 NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY) Roche Holdings, Inc. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [X] - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS WC - -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e). [ ] - -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- 7 SOLE VOTING POWER 15,089,742 shares of Common Stock NUMBER OF See Items 4 and 5 below. SHARES ------------------------------------------------------------ BENEFICIALLY 8 SHARED VOTING POWER N/A OWNED BY ------------------------------------------------------------ EACH 9 SOLE DISPOSITIVE POWER 15,089,742 shares of Common Stock REPORTING See Items 4 and 5 below. PERSON WITH ------------------------------------------------------------ 10 SHARED DISPOSITIVE POWER N/A - -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 15,089,742 shares of Common Stock See Items 4 and 5 below. - -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES [ ] - -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 44.0% of Common Stock See Items 4 and 5 below. - -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON CO, HC - -------------------------------------------------------------------------------- (Page 2 of 9 Pages)

The following information amends and supplements the Schedule 13D dated April 28, 1995, as previously amended (as so amended, the "Schedule 13D"). Unless otherwise indicated, each capitalized term used but not defined herein shall have the meaning assigned to such term in the Schedule 13D. Item 4. Purpose of Transaction On June 26, 2000, Holdings sold 500,000 shares of Common Stock in a brokerage transaction at a price of $72.30 per share, on June 27, 2000, Holdings sold 300,000 shares of Common Stock in a brokerage transaction at a price of $72.25 per share and on June 29, 2000, Holdings sold 1,700,000 shares of Common Stock in a brokerage transaction at a price of $75.67 per share. Item 5. Interest in Securities of the Issuer. (a) After giving effect to the sales described in Item 4, Holdings beneficially owns 15,089,742 shares of Common Stock, including 11,456,816 shares of Common Stock issuable upon conversion of the 6,301,255 shares of Series B Preferred Stock owned by Holdings. Based upon information provided by the Company as of June 6, 2000, the 15,089,742 shares of Common Stock beneficially owned by Holdings represent approximately 44.0% of the Common Stock outstanding (assuming conversion of the Company's preferred stock). (b) Except as set forth herein, no transactions in the Common Stock have been effected during the past 60 days by the Reporting Persons, any other person controlling any of the Reporting Persons or, to the best of the knowledge of the Reporting Persons, any of the persons named in Schedules A, B and C hereto, except that as described in Item 4, on June 26, 2000, Holdings sold an aggregate of 500,000 shares of Common Stock in a brokerage transaction at a price of $72.30 per share, on June 27, 2000, Holdings sold an aggregate of 300,000 shares of Common Stock in a brokerage transaction at a price of $72.25 per share and on June 29, 2000, Holdings sold an aggregate of 1,700,000 shares of Common Stock in a brokerage transaction at a price of $75.67 per share. Item 7. Material to be Filed as Exhibits 1. Executive Officers and Directors of Holdings, Finance and Roche Holding. (Page 3 of 9 Pages)

SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and accurate. Dated: June 30, 2000 ROCHE HOLDINGS, INC. By: /s/ Marcel Kohler ----------------------------------- Name: Marcel Kohler Title: Vice President, Controller and Secretary (Page 4 of 9 Pages)

Index to Exhibits Exhibit 99.1: Executive Officers and Directors of Holdings, Finance and Roche Holding. (Page 5 of 9 Pages)



                                                                   EXHIBIT 99.1

                                                                     SCHEDULE A

                      Executive Officers and Directors (*)
                                       of
                              Roche Holdings, Inc.

     The names of the Directors and the names and titles of the Executive
Officers of Roche Holdings, Inc. and their business addresses and principal
occupations are set forth below. If no address is given, the Director's or
Executive Officer's business address is that of Roche Holding Ltd which is
Grenzacherstrasse 124, 4002 Basel, Switzerland. Unless otherwise indicated,
each occupation set forth opposite an individual's name refers to Roche Holding
Ltd and each individual is a Swiss citizen.

Name, Business Address                      Present Principal Occupation
- ----------------------                      ----------------------------
* Dr. h.c. Fritz Gerber.....................Chairman of the Board and President
(President)

* Dr. Dr. h.c. Henri B. Meier...............Chief Financial Officer
(Vice President Finance and Treasurer)

Marcel Kohler...............................(Vice President Controller and
(Vice President, Controller and Secretary)  Secretary of Roche Holdings, Inc.)
One Commerce Center, Suite 1050
Wilmington, DE 19801


                               (Page 6 of 9 Pages)

SCHEDULE B Executive Officers and Directors (*) of Roche Finance Ltd The names of the Directors and the names and titles of the Executive Officers of Roche Finance Ltd and their business addresses and principal occupations are set forth below. If no address is given, the Director's or Executive Officer's business address is that of Roche Holding Ltd, which is Grenzacherstrasse 124, 4002 Basel, Switzerland. Unless otherwise indicated, each occupation set forth opposite an individual's name refers to Roche Holding Ltd and each individual is a Swiss citizen. Name, Business Address Present Principal Occupation - ---------------------- ---------------------------- *Dr. h.c. Fritz Gerber................Chairman of the Board and President (President) * Dr. Franz B. Humer..................Chief Executive Officer * Dr. Dr. h.c. Henri B. Meier.........Chief Financial Officer (Page 7 of 9 Pages)

SCHEDULE C Executive Officers and Directors of Roche Holding Ltd The names of the Directors and the names and titles of the Executive Officers of Roche Holding Ltd and their business addresses and principal occupations are set forth below. If no address is given, the Director's or Executive Officer's business address is that of Roche Holding Ltd, which is Grenzacherstrasse 124, 4002 Basel, Switzerland. Unless otherwise indicated, each occupation set forth opposite an individual's name refers to Roche Holding Ltd and each individual is a Swiss citizen, except that Mr. Brabeck-Letmathe is an Austrian citizen, Mr. von Prondzynski is a German citizen and Mr. Burns and Professor Knowles are citizens of the United Kingdom. Board of Directors Dr. h.c. Fritz Gerber Chairman Dr. Andres F. Leuenberger Vice-Chairman Dr. Rolf Hanggi Vice-Chairman Dr. Franz B. Humer Delegate Mr. Peter Brabeck-Letmathe Chief Executive Officer Nestle SA of Nestle Avenue Nestle, CH-1800 Verey Mr. Andre Hoffmann Businessman La Massellaz CH-1126 Vaux sus Morges Professor Kurt Jenny Attorney-at-law Aeschengraben 18 P.O. Box 3309 CH-4002 Basel Dr. Dr. h.c. Henri B. Meier Chief Financial Officer of Roche Holding Ltd. Dr. Andreas Oeri Surgeon Praxisgemeinschaft Clarahof Clarahofweg 19a CH-4005 Basel Professor Charles Weissmann University professor Neurogenetics Unit Imperial College School of Medicine at St. Mary's Hospital Norfolk Place London W1H 1TJ Great Britain Dr. Gottlieb A. Keller Secretary to the Board of Directors (Page 8 of 9 Pages)

Executive Committee Dr. Franz B. Humer Chairman, Head of Pharmaceuticals Division Dr. Dr. h.c. Henri B. Meier Finance Mr. Heino von Prondzynski Diagnostics Division Dr. Markus Altwegg Vitamins and Fine Chemicals Division Mr. William M. Burns Pharma International Operations Professor Jonathan Knowles Global Pharmaceutical Research Dr. Daniel Villiger Corporate Services Mr. Pierre Jaccoud Secretary to the Executive Committee (Page 9 of 9 Pages)