UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C. 20549

               STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

                                  FORM 4

[ ] Check this box if no longer                  OMB APROVAL
    subject to Section 16. Form 4 or             OMB NUMBER:  3235-0287
    Form 5 obligations may continue.             Expires: September 30, 1998
    See Instruction 1(b).                        Estimated average burden
                                                 hours per response........0.5

  Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
      Section 17(a) of the Public Utility Holding Company Act of 1935
          or Section 30(f) of the Investment Company Act of 1940

(Print or Type Responses)

1. Name and Address of Reporting Person*

    Roche Holdings, Inc.
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     (Last)                         (First)                      (Middle)

    1201 N. Orange Street, Suite 1050
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                                   (Street)

    Wilmington                     DE                               19801
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     (City)                         (State)                           (Zip)


2.   Issuer Name and Ticker or Trading Symbol

     Laboratory Corporation of America Holdings (LH)
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3.   I.R.S. or Social Security Number of Reporting Person (Voluntary)


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4.   Statement for Month/Year

     1/02
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5.   If Amendment, Date of Original (Month/Day/Year)


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6.   Relationship of Reporting Person(s) to Issuer   (Check all applicable)

       Director                                         X 10% Owner
    ---                                               ---

       Officer (give title below)                        Other (specify below)
    ---                                               ---

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7.   Individual or Joint/Group Filing (Check Applicable Line)

 X      Form filed by One Reporting Person
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        Form filed by More than One Reporting Person
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      Table I -- Non-Derivative Securities Acquired, Disposed of, or
                            Beneficially Owned


1.   Title of Security    2. Trans-  3. Trans-     4. Securities Acquired  5. Amount of Securities  6. Ownership      7. Nature of
     (Instr. 3)              action     action        (A) or Disposed of      Beneficially Owned       Form: Direct      Indirect
                             Date       Code          (D) (Instr. 3, 4        at End of Month          (D) or In-        Beneficial
                                        (Instr.8)     and 5)                  (Instr. 3 and 4)         direct (I)        Ownership
                             (Month/                                                                   (Instr. 4)        (Instr. 4)
                             Day/                         (A) or
                             Year)    Code    V    Amount   (D)    Price
- ------------------------- ---------   ----   ---   -------  --- ---------  --------------------     --------------    -------------
                                                                                                  




Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

                                                                          (Over)
                                                                 SEC 1474 (7-96)

FORM 4 (continued) Table II -- Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities) 1. Title of 2. Conversion or 3. Transaction Date 4. Transaction 5. Number of 6. Date Exercisable and Derivative Exercise Price (Month/Day/Year) Code Derivative Expiration Date Security of Derivative (Instr. 8) Securities (Month/Day/Year) (Instr. 3) Security Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) Date Expiration Code V (A) (D) Exercisable Date - ------------------------------------------------------------------------------------------------------------------------------------ - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 12/18/01 S 50000 6/21/02 6/21/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 12/19/01 S 51800 6/21/02 6/21/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 12/21/01 S 148200 6/21/02 6/21/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 12/21/01 S 250000 6/21/02 6/21/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 12/27/01 S 250000 6/21/02 6/21/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 1/14/02 S 10500 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 1/15/02 S 145000 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 1/16/02 S 250000 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 1/16/02 S 203000 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 1/17/02 S 47000 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 2/11/02 S 161250 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $75 2/12/02 S 93824 9/20/02 9/20/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 11/20/01 S 500000 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 11/21/01 S 50000 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 11/23/01 S 200000 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 11/26/01 S 65000 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 12/05/01 S 44000 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 12/13/01 S 28500 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 12/14/01 S 66300 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 12/17/01 S 46200 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) $80 2/11/02 S 250000 11/15/02 11/15/02 - ------------------------------------------------------------------------------------------------------------------------------------
1. Title of 7. Title and Amount of 8. Price of 9. Number of 10. Ownership 11. Nature of Derivative Underlying Securities Derivative Derivative Form of Indirect Security (Instr. 3 and 4) Security Securities Derivative Beneficial (Instr. 3) (Instr. 5) Beneficially Security: Ownership Amount Owned at End Direct (D) (Instr. 4) or of Month or Indirect Number (Instr. 4) (I) of (Instr. 4) Title Shares - ------------------------------------------------------------------------------------------------------------------------------------ - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 50000 $10.06 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 51800 $10.06 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 148200 $10.04 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 250000 $10.03 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 250000 $10.40 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 10500 $10.23 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 145000 $10.09 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 250000 $10.54 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 203000 $10.08 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 47000 $10.00 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 161250 $14.48 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 93824 $13.27 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 500000 $12.93 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 50000 $13.44 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 200000 $13.10 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 65000 $13.00 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 44000 $11.00 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 28500 $10.65 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 66300 $10.62 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 46200 $10.59 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Call Options (obligation to sell) Common Stock 250000 $12.92 0 D - ------------------------------------------------------------------------------------------------------------------------------------ Explanation of Responses: **Intentional misstatements or omissions of facts constitute Federal Criminal Violations. /s/ Marcel F. Kohler See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a) ------------------------------- ---------- **Signature of Reporting Person By: Marcel f. Kholer authorized signatory for Roche Holdings, Inc. Page 2 SEC 1474 (7-96)