Document


UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C.  20549

FORM 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

February 27, 2018
(Date of earliest event reported)

LABORATORY CORPORATION OF
AMERICA HOLDINGS
(Exact Name of Registrant as Specified in its Charter)
Delaware
 
1-11353
 
13-3757370
(State or other jurisdiction of Incorporation)
 
(Commission File Number)
 
(I.R.S. Employer Identification No.)

358 South Main Street,
 
 
 
 
Burlington, North Carolina
 
27215
 
336-229-1127
(Address of principal executive offices)
 
(Zip Code)
 
(Registrant’s telephone number including area code)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
[ ]
Written communication pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[ ]
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[ ]
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[ ]
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 7.01
Regulation FD Disclosure

Summary information of the Company dated February 28, 2018.

Exhibit Index


















SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

LABORATORY CORPORATION OF AMERICA HOLDINGS
Registrant

 
 
 
 
 
By:
/s/ F. SAMUEL EBERTS III
 
 
F. Samuel Eberts III
 
 
Chief Legal Officer and Secretary

February 27, 2018



investordaypresentation0
Investor and Analyst Day February 2018


 
2 Forward Looking Statement and Use of Adjusted Measures This presentation contains forward-looking statements including but not limited to statements with respect to estimated 2018 guidance and the related assumptions, the impact of various factors on operating and financial results, expected savings and synergies (including from the LaunchPad initiative and as a result of acquisitions), and the opportunities for future growth. This presentation contains forward-looking statements which are subject to change based on various important factors, including without limitation, competitive actions and other unforeseen changes and general uncertainties in the marketplace, changes in government regulations, including health care reform, customer purchasing decisions, including changes in payer regulations or policies, other adverse actions of governmental and third-party payers, changes in testing guidelines or recommendations, adverse results in material litigation matters, the impact of changes in tax laws and regulations, failure to maintain or develop customer relationships, our ability to develop or acquire new products and adapt to technological changes, failures in information technology systems or data security, challenges in implementing business process changes, employee relations, and the effect of exchange rate fluctuations on international operations. Actual results could differ materially from those suggested by these forward-looking statements. The Company has no obligation to provide any updates to these forward-looking statements even if its expectations change. Further information on potential factors, risks and uncertainties that could affect the operating and financial results of Laboratory Corporation of America Holdings (the “Company”) is included in the Company’s Form 10-K for the year ended December 31, 2016, and subsequent Forms 10-Q, including in each case under the heading risk factors, and in the Company’s other filings with the SEC. This presentation contains “adjusted” financial information that has not been prepared in accordance with GAAP, including Adjusted EPS, and Free Cash Flow, and certain segment information. The Company believes these adjusted measures are useful to investors as a supplement to, but not as a substitute for, GAAP measures, in evaluating the Company’s operational performance. The Company further believes that the use of these non-GAAP financial measures provides an additional tool for investors in evaluating operating results and trends, and growth and shareholder returns, as well as in comparing the Company’s financial results with the financial results of other companies. However, the Company notes that these adjusted measures may be different from and not directly comparable to the measures presented by other companies. Reconciliations of these non-GAAP measures to the most comparable GAAP measures are included in this presentation.


 
Dave King Chairman and Chief Executive Officer Enterprise Strategic Overview


 
Who We Are Our Mission is to Improve Health and Improve Lives LabCorp is a Leading Global Life Sciences Company that is deeply integrated in guiding patient care Our Strategic Objectives are to: Deliver World-Class Diagnostics Bring Innovative Medicines to Patients Faster Use Technology to Improve the Delivery of Care 4


 
A Sound Foundation Supports the Combination 1 Creates powerful life sciences enterprise with a market opportunity of over $200 billion 3 2 Expands growth opportunities for Diagnostics and Drug Development businesses Capitalizes on strengths to create a differentiated offering 5


 
Opens Attractive Growth Opportunities Across Multiple Global Markets U.S. Clinical Lab Testing Market ~$80 billion Global Addressable Outsourced R&D Spend ~$35 billion Global Addressable Market ~$200 billion LH Ex-U.S. Clinical Lab Testing Market ~$100 billion Ex-U.S. Clinical Lab Opportunity LH(1) ~9% Source: Industry reports and company estimates 1. Includes 12-month estimate of Chiltern revenue on a proforma basis ~10% ~5% Leadership in Large, Growing, Fragmented Markets LH(1) U.S. Clinical Lab Opportunity Global CRO Opportunity LabCorp Enterprise Growth Opportunity 6


 
Creates a Differentiated Offering to Better Serve All Healthcare Stakeholders 7 • Patient database reaching ~50% of U.S. population • Proprietary data sets with >30 billion lab test results across a growing menu of nearly 5,000 assays • Broad physician, health system and managed care relationships • Consumer engagement through ~1,900 PSC/retail locations, 5,000+ in-office phlebotomists • Proprietary decision-support and reporting tools • Serving the top 20 biopharma • Serving high-growth emerging and mid-market segments through Chiltern • Working on ~50% of clinical trials • >175,000 unique investigators • Involved in all top 50 best-selling drugs on the market • Supported 70% of all CDx on the market today • Robust technology suite for trial planning and execution • Global footprint with business in 127 countries; 60,000 employees • Unmatched real-world data and patient intelligence • Deep scientific and therapeutic experience • Leader in Companion Diagnostics (CDx) • Innovative technology-enabled solutions for customers LabCorp Diagnostics Covance Drug Development


 
2018 Priorities Drive Profitable Growth Optimize Enterprise Margins Integrate Key Acquisitions 8


 
Transition to Value-Based Care Enhance the Drug Development Process Embrace the Role of the Consumer • Improve efficiency in care delivery • Reduce the overall cost of patient care • Utilize advanced tools and analytics to deliver better outcomes via personalized medicine and population health • Address increased trial complexity, and competition for patients and investigators • Greater need for scalable tools and processes to initiate and manage trials • Increased sponsor demand for data-driven study design and execution, as well as access to relevant analytes, biomarkers and tests • Increased interest in and influence over healthcare decision-making • Technology advances driving expectation of convenience • Consumer satisfaction increasingly important to other healthcare stakeholders Strategic Initiatives to Capitalize on Long-term Market Opportunities 9


 
28% Patients Seen in Denver LabCorp at Walgreens 2016 >$200 million 2017 ~$500 million Value-Based Care Solutions Streamlining Clinical Studies Consumer Platform Completed 3 marquee transactions in 2017 Cumulative new orders won through the combination of LabCorp patient data and Covance capabilities: On track to deliver $150 million in cumulative new revenue from the acquisition of Covance through 2018 Patients new to LabCorp LabCorp PSCs in Walgreens stores are attracting new patients Reference Laboratory Testing Outreach Laboratory Testing Inpatient Laboratory Management PAML and its Joint Venture Interests Mount Sinai Health System Novant Health Differentiated Solutions are Resonating with Customers 10


 
Creates Long-term Shareholder Value $4.1 $4.5 $4.7 $5.0 $5.5 $5.7 $5.8 $6.0 $0.0 $2.0 $4.0 $6.0 $8.0 $10.0 $12.0 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 $8.5 $9.4 $10.4 $2.3 $2.8 $3.6 $6.2 $6.6 $6.9 (1) 2007-2014 revenues excludes Covance results. 2008 revenue includes a $7.5 million adjustment relating to certain historic overpayments made by Medicare for claims submitted by a subsidiary of the Company (2) Includes the estimated impact from adoption of the new revenue recognition accounting standard (ASC 606). See Appendix for details of the preliminary reconciliation of 2017 results 10-Year CAGR: 10% • Record revenue of $10.2B • Record EPS of $9.60 • Record free cash flow of $1.1B • 24% increase in share price Record 2017 Results 2018 FORTUNE World’s Most Admired Companies 2017 FORBES World’s Most Innovative Companies Drug Development Diagnostics (In Billions) Revenue(1) (2) 11


 
LabCorp is Well Positioned for Future Growth Financial Strength and Flexibility Quality and Service Stable and Global Business Innovation Multiple Avenues for Future Growth 12


 
John Ratliff Chief Executive Officer, Covance Drug Development Jonathan Koch Group President of Clinical Development and Commercialization Services, Covance Drug Development Covance Drug Development Strategic Overview


 
14 The Drug Development Landscape Strong Market Trends and Client Demand Improving regulatory environment Venture funding remains solid Significant innovation in emerging biotech segment Total Molecules 8,837 Total Molecules 11,197 Total Molecules 12,500 Total Molecules 13,454 Strong therapeutic growth, especially in oncology 3% 8% 9% 11% 29% 31% 31% 36% 13% 3% 4% 6% 55% 58% 56% 47% 2013 2015 2016 2017 Other Cardiovascular & Metabolic Disorders Oncology Rare Diseases


 
15 2017: A Transformative Year Addressing Challenges and Positioning for Growth Talented Team, Enhanced Capabilities, Process Efficiency Enhanced Tools and Technology Chiltern Integrated Capabilities Deeper Executive Talent Bench and International Expansion Book to Bill 1.36 LaunchPad Business Process Improvement Initiatives Key Solution Launches (Companion Diagnostics, Biomarkers, Biotech, etc.)


 
EXTRAORDINARY POTENTIAL EXCEPTIONAL PEOPLE ENERGIZING PURPOSE 16 Covance Growth Strategy Leveraging LabCorp/Covance Combined Strength, Utilizing Market Leading Assets, Demonstrating Clinical Leadership, Maximizing Tools and Technology NOW Strengthen & Expand NEXT Grow & Deepen NEEDED Evolve & Lead ►Broaden Scientific Leadership ► Increase Patient-Centered Solutions ►Expand Core Services ►Portfolio Management and Monitoring ►Create Best-in-Class Patient Recruitment and Site Management Through Data ►Expand Global Delivery ► Launch Biotech Differentiated Offering ►Enter Adjacent Markets ► Lead Virtualization of Clinical Trials ►Apply Patient-Centric Technologies ►Embrace Alliances with New Partners ►Evolve Informatics and Analytics IMPROVE HEALTH, IMPROVE LIVES ADVANTAGES: SCIENCE PATIENT CENTRICITY LOGISTICS DATA DISCOVERY DEVELOPMENT COMMERCIALIZATION Research Preclinical Phase I Phase II Phase III Phase IV RWE GROWTH STRATEGY EMPLOYEES PATIENTS INVESTORS CUSTOMERS


 
17 Leveraging LabCorp-Covance Combined Strength Unique Offerings and Differentiated Value Patient-Centered Solutions and Data Insights Scientific Collaboration (e.g., Companion Diagnostics, Real World Evidence) LaunchPad Business Process Improvement Initiatives


 
18 Leveraging LabCorp-Covance Combined Strength Unique Patient-Centered Solutions and Data Insights Empowered patients are searching for treatment alternatives and choosing to participate in clinical studies Real world data is used to find the right patients for a clinical study Matching patients’ physicians who have a pre-existing relationship with LabCorp enables more meaningful conversations Known Covance investigators are identified around clusters of matching patients The data identifies where the patients are, who they are, and who their physicians are Covance can reach out to patients directly, as well as contact physicians to inform them about specific patients who may be eligible for a given study Granular, structured, real world lab data is collected and readily available for Covance’s use Empowered Patients “Choosing to participate” Real World Lab Data Largest in the world The Right Patient LabCorp Data, Investigators Matched Patients Who and where they are…


 
19 Leveraging LabCorp-Covance Combined Strength Holistic Approach to Patient Intelligence Protocols / Trial Insights / Clinical Labs Data LabCorp Patient Data Patient Survey / Voice of Patient ► ~115 million patient encounters annually ► ~1,900 patient service centers ► High-quality data, including diagnosis codes, demographics and lab results ► Covance supports ~50% of all clinical trials ► >50 million global patient lab results per year from central lab network Patient Intelligence ► >200,000 patients have requested to be notified by Covance about relevant clinical studies; focused on increasing participation rate ► Obtaining actionable patient insights regarding trial participation


 
20 Leveraging LabCorp-Covance Combined Strength Scientific Collaboration with Market Leading Companion Diagnostics (CDx) Capabilities ► Supported more than 300 CDx, in vitro diagnostic and medical device studies ► Collaborated with over 40 clients on more than 165 CDx projects in 2017 ► CDx-related net orders grew ~4x from 2015 to $244M in 2017 ► ~$135M in CDx-related enterprise revenue in 2017; 3-year CAGR of ~20% Drug Development Biomarker/CDx Development Biomarker Development CDx Assay & Feasibility CDx Development & Validation Regulatory Submission & CDx Launch Preclinical Phase I Phase II Phase III NDA Submission Covance Provides Comprehensive CDx Solutions For The Drug Life Cycle Commercialization


 
21 Utilizing Market Leading Assets As an Example… Central Laboratory Services


 
Expanding Clinical Capabilities Stronger Together with Chiltern Presence • Broad customer base with strong growth potential across all segments Therapeutic Capabilities • Broad therapeutic offering across all phases of development • The most experienced central laboratory (e.g., biomarkers, companion diagnostics) Informatics • Clinical analytics and FSP capabilities and suite of technology offerings (Xcellerate® and Endpoint IVR) People • Global employee enhancement • Dedicated teams • Collaborative engagement • Personalized attention • Data aggregation and insight • Deep therapeutic and scientific expertise Combined Offering Delivers Value Biotech: Delivering A Differentiated Experience • Early Phase Development Solutions • Phase I Sites/Adaptive Design • Phase I-IV • Biomarkers/CDx • Central Lab/Esoteric testing • Consulting Regulatory Commercial • Covance MarketPlace • Xcellerate Providing Industry Leading Breadth of Solutions 22


 
23 LaunchPad Business Process Improvement Initiative Re-engineering Processes and Integrating New Technology to Drive Margin Expansion Net Savings: $20M in 2017, and additional $130M over three years ending in 2020 After achieving $100M in cost synergies from LabCorp's acquisition of Covance Talent and Asset Optimization Process Discipline and Productivity Delivery Transformation Customer Centricity • Process and system improvements • Culture of continuous process improvement • Aligning people and capabilities with client expectations • Optimizing the global footprint • Transforming the delivery of clinical studies and lab services • Positioning the company for the future of clinical trials • “Customer First” mindset • Driving growth and loyalty through customer-centric investment • Global service delivery model (GSDM) • Organizational design to enable seamless distribution of work globally • Real estate consolidation • Commercial process investments and improvements • Differentiated, integrated solutions from Chiltern acquisition • Software-enabled process automation • Rollout of new technology platforms


 
Reduces the time, cost and risk of specimen based research. 24 Maximizing Tools and Technologies Innovative Solutions Focused on Client Needs Contributed to $1B+ of Revenue Across Clinical Development in 2017


 
Key Takeaways 25 Diagnostics and Drug Development combination creates differentiation from competition through data, patient intelligence, and scientific collaboration Transformative investments in talent, solutions, and technology positioning Covance for growth Strong book to bill of 1.36 and backlog of over $7.1B driving year-on- year revenue growth of 20% - 24% (mid to high single digit organic growth), including improved margins over the next 3 years


 
LabCorp Diagnostics Strategic Overview Gary Huff Chief Executive Officer, LabCorp Diagnostics


 
27 LabCorp Diagnostics At-a-Glance Expertise • Unmatched depth and breadth of solutions • Scientific, therapeutic, value-based care and IT expertise • Experienced senior leadership • 11 Centers of Excellence • ~600 M.D. and Ph.D. Financial Strength • Significant free cash flow • Stable business with history of performance • >$7 billion in revenue in 2017; 10-year revenue CAGR of ~6% • Hundreds of thousands of client relationships • ~1,600 managed care contracts Market Position • Leading scientific innovation and ability to partner and acquire expertise • Value creation with diagnostics and drug development combination Why customers choose LabCorp • We lower cost and improve quality • We create value with the combination of Diagnostics and Drug Development • We are focused on providing an exceptional experience Infrastructure • Strong U.S. infrastructure • ~1,900 Patient Service Centers • Extensive test menu, including esoteric offering • 3,100 couriers • ~50% of U.S. population in patient database • >65,000 digital interfaces


 
28 Creating Differentiated Value for our Consumers, Customers, and Employees Multiple Growth Opportunities • Health systems and hospitals • Managed care • Independent physicians • Companion diagnostics Data Powerhouse with IT Expertise • ~50% of U.S population / >30 billion lab test results • Big data platform • Interfaces with over 600 EMR and laboratory information systems (LIS) vendors • Holistic approach to patient engagement, including mobile Continual Innovation • Venture investments • Walgreens retail health partnership • Proprietary technology to enhance the consumer experience • 100 new tests per year (on average) Leadership • Talented leadership, track record of execution • Scientific strength • Consistent, profitable growth • Structured to be close to the customer


 
29 Leadership in a Stable, Growing, and Fragmented Market LabCorp, $7B Quest Diagnostics, $8B Independent Labs, $13B Hospital Labs, $47B Physician Office Labs, $4B Independent Labs, $13B Hospital Labs, $47B Physician Office Labs, $4B Market dynamics are creating opportunity $27B Inpatient & Outpatient (1) $17B Outreach $3B Reference ~$80 billion U.S. Lab Market Historically difficult to penetrate (1) Generally reimbursed as part of a bundled payment Hospital Lab Testing Market


 
Well-Positioned to Capture the Addressable Market Physician Office Labs Hospital Outreach and Reference Labs Independent Labs Addressable Market $37B Driving Profitable Growth Deliver innovative value-based care solutions Accretive and strategic acquisitions Value creation through diagnostics and drug development combination 1 2 3 $4B $20B $13B 30


 
31 Multiple Industry Dynamics Play to LabCorp’s Strengths Consumerism • Consumers are taking greater responsibility for their wellness and healthcare • Demand low cost, high quality, access and technology • Access: Partner with health retailers • Convenience: consumer initiated programs and in-home testing Scientific Innovation • Personalized medicine guiding new approaches • Next generation sequencing capability • OmniSeq partnership for molecular profiling to improve cancer treatment Technological Innovation • Technologies are developing rapidly and require capital to employ • Big data platforms needed to connect information from disparate sources • EHR data fed into analytics platform for predictive learning Pricing Pressure • Insurers are focused on driving utilization to low-cost site of care • National scale enables low-cost position • Automation and standardization provide industry-leading operational efficiency


 
Drive Profitable Growth 32 Optimize Opportunities − Acquisition Integration − Bad Debt Improvement − LabCorp at Walgreens Expansion 1. 2. 2018 Diagnostics Priorities


 
33 Driving Growth Through Focus on Key Customer and Testing Segments Accretive and strategic acquisitions Leverage combination of diagnostics and drug development Deliver innovative value-based care solutions How Will We Grow? Smart Growth Customer Segments Testing Segments Physician Groups Managed Care Health Systems Consumers Genetics Oncology Medical Drug Monitoring Women’s Health Rare and Orphan Diseases


 
34 Utilizing Technological Innovation to Improve Care, Lower Cost and Enhance Experiences Improve Care • Value-based care solutions and tools • Laboratory analytics and decision support tools 1 Lower Cost, Improve Quality 2 Enhance Experiences 3 • Automation expansion, including Propel • Standardization • IT connectivity • Roll-out of consumer self-service tools • Meet patients where they want to be met • Price transparency


 
35 Key Takeaways Well-positioned for long-term profitable growth through our differentiated laboratory solutions and combination with Drug Development capabilities Committed to quality, service and innovative solutions providing the foundation for new and deeper collaborations with customers Lab market undergoing unprecedented changes driven by consumerism, scientific and technological innovation, as well as price pressure


 
Brian Caveney, M.D. Chief Medical Officer Bryan Vaughn Senior Vice President, Health Systems, LabCorp Diagnostics Broad Capabilities that Support the Transition to Value-Based Care


 
37 Value-Based Care is an Evolution Health Systems Deep, innovative partnerships Clinicians Efficient workflow, timely information Payers Data sharing, provider collaboration The transition is complex and iterative Accurate and timely diagnoses play a critical role Fee-for- service Value- based


 
38 Uniquely Positioned to Succeed in Value-Based Care Powered by standardized lab systems and data, flexible data interfaces and feeds, and technology-enabled tools Lower Cost of Utilization • Managed care networks, benefits • Health system partnerships • Consumer empowerment Right Test, Right Patient • Smart test design (i.e., cascades) • M.D., Ph.D. access • Cover gaps in care • Result trending, global result search Beyond Lab Testing • CDx, CaDx for optimal therapy • Chronic disease programs with clinical decision support • Data supports care management programs and population health • Access to clinical trials


 
39 Offering Leading, Broad-Based Solutions in Value-Based Care Leading Laboratory Services • National access • Comprehensive test menu • Sales and service organization • Scientific innovation • Power of scale Payer and Provider Collaboration • Help stakeholders achieve total cost of care metrics in value-based care contracts • Actionable lab results • Global patient results data • MACRA, HEDIS, and ACO quality metrics • Care Intelligence® population health Clinical Decision Support • Programs on key disease states • Lab reports support care guidelines • Developed by physicians • Data monitoring drives cost-effective care management Drug Development Solutions • Companion diagnostics leadership • Potential provider revenue stream from increased participation in clinical trials • Cost savings to patients and payers • “Real World” data


 
40 Actionable Data for Every Stakeholder Providers • Identifies untreated problems • Patient-specific recommendations based on current guidelines / standards of care delivered with lab results Payers • Targeted data feeds • Lower overall medical expenses through earlier disease identification Patients • Educate patients about what their lab results mean • Empower patients to participate in their own care • Condition-specific care plans Care Management Team • Real-time targeting of high risk patients • Highlight outliers and likely gaps in care • Metrics on provider performance


 
41 Driving Value Through Broad-Based Partnerships with Health Systems Highly Efficient Lab Provider Positioned for value-based care and consumer driven future Redeploy Capital, IT, Time Clinical Trials Participation Innovation Leverage Quality, Programs and Tools Simplification and Standardization


 
42 Health Systems Opportunity Value-based care will drive today’s fee-for-service settings to look more like cost centers Hospitals Post-acute Alt Sites Specialists Primary Care $47B Hospital Labs $4B Physician Office Labs Multi-billion dollar opportunity in health system partnerships driven by LabCorp’s low-cost, high- quality market position PAMA and new technology will drive unprecedented transparency


 
43 Major Academic Health System Case Study Case Study Multi-faceted relationship with Mount Sinai Health System Outreach Acquisition • Divesture of non-core asset • Gained square footage by reducing infrastructure Reference Testing • Consolidation of lab partners • Reduces expense, IT, and complexity Data for Accountable Care • Sharing standardized lab result data to empower population health • Innovative Hepatitis C awareness and management program under development Academic Collaboration • Carved out molecular / genetics lab from acquisition • Support of residency programs Clinical Trials • ↑ number of studies offered by Covance Financial Benefits • Redeploy capital, space, and IT resources • Operations improvement through efficiencies and trials


 
44 Innovation with Health Systems to Help Improve Patient Care


 
45 Multi-Pronged Approach to Deliver Value to an Accountable Care Organization (ACO) Clinically integrated network with 240 physicians Multiple EHRs, multiple value-based contracts Case Study Deployed Care IntelligenceTM population health tool Standardized, timely lab result data High quality, cost effective lab service In 2016, for 16,000 commercial patients: • $4.7M in total savings • ↓ inpatient utilization 15% • ↑ primary care visits double digits in high risk patients • 90th percentile patient satisfaction High-cost and out-of- network lab providers High risk and rising risk patient populations Active patient management


 
46 Key Takeaways Developing innovative tools, technology and business models to further our value proposition for patients and health systems Supporting health systems’ transition to value-based care represents a multi-billion dollar long-term growth opportunity Uniquely positioned to succeed in value-based care by lowering the cost of utilization, driving appropriate utilization, and providing value beyond lab testing


 
Extending our Leadership in Companion Diagnostics Marcia Eisenberg, Ph.D. Chief Scientific Officer, LabCorp Diagnostics Steven Anderson, Ph.D. Chief Scientific Officer, Covance Drug Development


 
48 Precision Medicine and Companion Diagnostics (CDx) 21% 28% 27% 34% 2014 2015 2016 2017 Personalized Medicines Top 30% of FDA Approvals for First Time in 2017(1) Key Drivers in Precision Medicine ► Genomic and proteomic biomarkers are key features of developing new therapies and diagnostics • Define the disease biology • Provide targets for new therapies ► A companion diagnostic is the ultimate biomarker test • Co-developed and linked with a specific therapy • Help identify patients most likely to respond • Help identify patients who may have an adverse event • Provide added value for how the diagnostic and therapy are used (1) Source: Personalized Medicine Coalition. Personalized Medicine at FDA: 2017 Progress Report.


 
49 Two Decades of Experience with CDx Commercialization 1998 2002 2006 2012 2016 2017 Validation and launch of HerceptTest First commercial launch of EGFR Mutation Analysis Validation and launch of ALK for NSCLC Launch of COBAS EGFR V2 Plasma Launch of Thermo Fisher Oncomine Dx Target Test Validation and launch of BRAFV600E for melanoma Validation and launch PD-L1 by IHC for nivolumab and pembrolizumab in NSCLC Covance / LabCorp CDx Facility


 
50 Unmatched Franchise Providing End-to-End Clinical Development and Commercial Lab Testing Solutions Commercialization a t o r y A pp r o v a l Cli n i c a l U t ili t y Drug Development Biomarker/CDx Development Preclinical Phase I Phase II Phase III NDA Submission Biomarker Development CDx Assay & Feasibility CDx Development & Validation Regulatory Submission & CDx Launch ► Bench to commercialization expertise ► Leaders in both in vitro diagnostic (IVD) and single lab PMA regulatory approaches ► Experience with 300+ IVD and medical device studies ► Supported approximately 70% of all FDA approved companion diagnostics on the market – including approvals for HER2, KRAS, EGFR, BRAF, ALK and PD-L1 • Recent examples in immuno-oncology, liquid biopsy and next generation sequencing End-to-end capabilities are a differentiator for development, trial support and commercialization


 
51 Dedicated CDx Laboratory Combines Unmatched Expertise with Leading Technology ► 36,000 sq. ft. facility in North Carolina ► Dedicated laboratory and staff for development, validation, and transfer of CDx assays • Focus on Genomics and Molecular Pathology • Associated GMP manufacturing capabilities


 
Two CDx Solutions Enable Flexible Collaboration with Customers 52 Pharma IVD CRO CDx Partnership Single Site Pathway (ssPMA) ► Faster route for development and commercialization ► Develop and validate test on established IVD platform ► Laboratory service provider also leads the regulatory submission for regulatory clearance ► Initial launch as FDA-approved PMA IVD contingent on intended use of marker ► May subsequently partner with IVD manufacturer for kit development on same platform, allowing decentralization of testing Current projects are split 75% IVD partnership pathway and 25% ssPMA pathway, with a growing interest in the ssPMA approach IVD Pathway


 
53 Strong Demand for Companion Diagnostics Will Drive Profitable Revenue Growth $55 $106 $244 $0 $100 $200 $300 2015 2016 2017 $114 $153 $300 $0 $100 $200 $300 2015 2016 2017 CDx-Related Net Orders ($M) CDx-Related Backlog ($M)


 
End-to-End Support for a New Oncology Therapy and Associated CDx Assay 54 For a recently approved immuno-oncology therapy, Covance and LabCorp Diagnostics collaborated to provide five distinct drug development services: Demonstration of end-to-end capabilities that are a differentiator in Companion Diagnostics Case Study Drug Development Preclinical Phase I Phase II Phase III NDA Submission Research Commercialization Prepared drug to go into man (first in human dosing) Covance BioPharm CMC assisted in the manufacture and qualification of drug lots PK / PD support in early Phase I studies Covance pre-clinical pharmacokinentic and pharmacodynamic work Biomarker evaluation to enroll patients in pivotal clinical trials Covance Central Lab expertise supporting targeted clinical trial participants Commercialized assay development LabCorp Diagnostics ensured that the diagnostic was prepared and commercially available simultaneous with the drug’s launch Post-approval CMC to verify quality of the manufactured product for its intended audience


 
Comprehensive commercial strategy, including global CDx partnerships Interest in and use of the single site PMA regulatory approach drives improvements in efficiency, flexibility and cost Technological advancements enabled by multiplexing, such as Next Generation Sequencing, Gene Expression Profiling, and Proteomics Attractive expansion of client base – collaborating with mix of large pharma, emerging pharma and biotech clients Increasing interest in precision medicine and use of biomarkers extending beyond oncology to other therapeutic areas Capitalizing on Multiple CDx Growth Drivers 55


 
Key Takeaways 56 An increasing focus on precision medicine, with expansion beyond Oncology applications, provides a significant growth opportunity in CDx Dedicated resources and flexible approaches to CDx development allow Covance and LabCorp to provide solutions that meet client needs LabCorp and Covance have an unsurpassed track record in the development and commercialization of CDx assays


 
Break


 
Unmatched Data, Powerful Insight Lance Berberian Chief Information Officer Gabriela Feldberg Head of Feasibility, Recruitment and Engagement, Covance Drug Development


 
59 Compelling Combination of Data and Tethered Relationships is a Key Competitive Advantage for the Enterprise Our Data • Timely • Standardized • Precise • Identified Our Relationships • Patients • Physicians and Health Systems • Investigators • Pharmaceutical Companies • EMR Providers Actionable • Assist with Closing Gaps in Care • Recruit Patients Faster • Design High Quality Trials • Leverage Health System Data • Support Precision Medicine Goals


 
60 Covance Offers a Suite of Differentiated Drug Development Tools for Trial Planning and Execution • Metrics and Benchmarking • Trial Forecasting • Clinical Data Hub • Monitoring Solutions • Data Management • Insights • GlobalCODE • snapTRACK • LabCODE • Pulse • Drive cellerate®


 
61 LabCorp Diagnostics Offers Tools That Serve Key Customer Segments Service Physicians / Health Systems Consumers Payers / Managed Care Guidance on Test Selection Placement of Electronic Orders (Portal and EMR) Mobile Optimized Reservations Multi-Channel Check-In Delivery of Electronic Test Reports (Portal and EMR) Post-Analytical Clinical Decision Support Population Health (Data Feeds and Tools) Test Result Trending Client Supplies Ordering Online Invoice Payment Hospital Reporting Payer Reporting


 
Power of the LabCorp Data for Trial Design, Site Selection, and Patient Recruitment Real World Data • Not biased and represents people as they live with their disease • Patient data is granular and identifiable Vast Test Menu • 30+ billion test results across thousands of diagnostic assays • >2.5 million samples collected (>30% by LabCorp phlebotomists) and processed weekly across many diseases and therapeutic areas Population Level Disease Analysis • Surveillance of disease spread to enable just in time recruitment • Unlike other types of real world data, lab data can be easily accessed near real time 62


 
Covance supports ~50% of all clinical trials Power of the Xcellerate Investigator Database Number of Patients Date of First Patient In Quality Lab Cancellations and Queries Standardized Site Rank > 175,000 unique investigators > 15,000 unique protocols Investigator Performance Database 63


 
Case Study 64 Covance Value Proposition Exceeding Recruitment Goals for a Global Multi-Study Registration Program UNIQUE SOLUTIONS CLIENT CHALLENGE Randomize 2,700 patients within a very narrow timeframe for a suite of registration studies Get all sites across the globe up and running as quickly as possible Leveraged Xcellerate® historical investigator database to identify and secure highest performing investigators in indication >175k unique investigators >15k protocols Based on extensive feasibility outreach and site capacity assessment, efficiencies were identified that allowed effective overlapping of sites across the program resulting in accelerated site start-up and reduced clinical costs Key Performance Result: Achieved “first patient in” requirement ahead of schedule for all studies in the program. Beat historical industry performance across a number of key metrics: 18% fewer weeks from final protocol to FPI 75% more high-performing sites 31% more patients/site/month 41% fewer non-performing sites


 
Ulcerative Colitis Example 65


 
Understanding the Impact of Study Design on the Available Patient Pool 51,814 patients between June 2016 and May 2017 identified 48,708 patients between 18 and 80 years old 20,288 without Crohn’s Disease, IBD and UC Proctitis 20,146 without Malignancy, Inherited Immuno Syndrome, TB and HIV/AIDS 20,075 without Hepatitis B and C 13,950 with all relevant labs populated 13,750 with Neutrophil value >= 1.5x10^9/L and Platelet >=100x10^9/L 13,552 with Hemoglobin >= 8.5g/dL and Lymphocyte >500 cells/uL 13,516 with Total WBC >=3.0 x 10^9/L and Serum Creatine <=2xULN 13,227 with Alk Phos <=2xULN and ALT <=2xULN 12,980 with AST <=2xULN and Bilirubin <=3xULN The protocol inclusion / exclusion criteria is applied to the patient pool and then matching patients are geo-located on the map 66 75% reduction


 
Covance Data Insights Show Workload of Key Investigators # Active Studies # Investigators Patients Per Investigator 9+ 28 72 5-8 63 33 4 123 87 2-3 169 15 1 644 10 0 27 11 • Objective site performance data around the globe which includes 8+ pharma programs and 53 active UC studies • Creates immediate 963 sites for targeted outreach • 27 out of 1,054 (3%) of known investigators are not in an active trial • Investigator patient accrual per study drops as more studies are taken on – diminishing return from in-demand sites 67


 
Location of Covance Sites in Relation to Ulcerative Colitis Patients 68 Sample from Seven UK GP Surgeries BLUE DOTS – Crohn’s and UC Patients from EMR SIZE OF BLUE DOTS – Number of Patients STARS – Covance sites COLOR OF STARS – Green high score to red low score DOTS – UC patients who match study design from LabCorp Real World Database STARS – High performing Covance sites


 
Case Study 69 LabCorp/Covance Value Proposition Protocol Design to Maximize Patient Enrollment Opportunity UNIQUE SOLUTIONS CLIENT CHALLENGE Result: The eligible patient population increased by more than 50% without compromising the objectives of the trial Study to test if a drug reduced progression of kidney disease in patients with Type II diabetes Analyzed LabCorp de-identified patient data to discern whether small protocol changes could accelerate recruitment Data helped to identify that making minor changes to the eGFR cutoff would increase the patient pool size therefore reducing recruitment timelines >150 Million patients >30 Billion test results > Study was looking for a small subset of patients which represented <7% of patients


 
70 LabCorp/Covance Value Proposition Rescued Patient Enrollment for a Study of a Rare Mutation Leveraged LabCorp database with de-identified health information on patients with the rare mutation UNIQUE SOLUTIONS Seeking patients with AML and a rare genetic mutation <15% of AML patients CLIENT CHALLENGE Result: With 274 sites across 28 countries, patient enrollment is on now on track for the initial milestone and has regained its advantage in the recruitment competitive landscape Difficulty identifying available sites as landscape changed rapidly driving increased competition Pharma’s preferred sites were unavailable Increased recruitment activities in the US leveraging the LabCorp sales force to reach out to physicians to gauge interest as investigators and to recruit AML patients >150 Million patients Case Study


 
Case Study 71 LabCorp/Covance Value Proposition Piloting a Virtual Real World Evidence Study Developed a cross-enterprise virtual study model leveraging the Covance patient support call center, local LabCorp Patient Service Centers and Covance Central Labs to screen participants, collect lab specimens and analyze lab results, respectively • Online screening, e-consent and enrollment • Call center acting as virtual site coordinators • Fully integrated project oversight and data management UNIQUE SOLUTIONS CLIENT CHALLENGE Result: Conducted two successful pilot studies recruiting 315 patients across 65 Patient Service Centers. The pharma company is planning to scale up 10x from the pilot to a full national model. Develop a less costly, “site-less” approach to conduct a study collecting survey and laboratory data 65 LabCorp Patient Service Centers in the Pilot Study needed to be national in scope while reducing the patient travel burden


 
Setting Up for Long Term Success 72 Continuing to add real world data sources to further accelerate patient recruitment Driving a higher volume of patients through fewer sites by leveraging deep relationships with key health systems Utilizing LabCorp’s large network of Patient Service Centers to conduct virtual studies dramatically reduces the patient burden Leveraging rapidly growing LabCorp patient database to gather actionable patient insights to inform study design and execution


 
Key Takeaways 73 Direct engagement through multiple channels with patients, physicians, investigators, and health systems create a holistic data strategy Significant ongoing investment in talent, technology and capabilities will increase the power of our differentiated data and informatics Unmatched combination of patient and investigator data, which is the right data to guide the delivery of care, study design, site selection and patient recruitment


 
Accelerating the Consumer Innovation Platform Tom Kaminski Senior Vice President, Corporate Strategy Mark Wright Senior Vice President, Customer Products, LabCorp Diagnostics


 
75 44% 42% 28% 5% 2% 36% 33% 30% 7% 10% 17% 23% 33% 84% 84% Not sure No Influence Influence Primary 2017 LabCorp Consumer Study N=1,500 MOE +/- 2.5% Who is involved in the decision on where to get your lab testing (e.g. hospital lab vs. third-party commercial lab) • Consumers are taking greater responsibility for their wellness and healthcare • Experiencing higher co-pays and deductibles, consumers are increasingly influential in the decision on where lab testing is performed • Advances in technology drive expectation of convenience • Performing testing for >2.5 million consumers per week and seeing >150,000 consumers per weekday in person, LabCorp is uniquely positioned to engage with health care consumers at scale • Having diagnosis and test result information, LabCorp has data and clinical expertise to engage with consumers in a personalized manner Why Focus on Patients as Consumers?


 
76 Organizing Around the Empowered Consumer Convenient and Flexible Options “It is easy to get the lab testing I want or need in the setting that I choose.” Access and Insights “I understand my results in the context of my overall health. I manage my health information and decide when and how to share it.” Price Transparency “I understand the relative prices of different lab service providers to make an informed choice. I know what I will pay before I receive services.” Engagement “I engage with the brand on my terms and receive valuable, personalized content. My feedback is heard and acted upon.”


 
Consumer Engagement is a Priority • Capturing e-mail and mobile phone numbers for LabCorp consumers across multiple touch points to enable richer engagement and customer satisfaction • Continue to directly engage with patients through online appointment scheduling, automated check-ins, as well as electronic delivery of results and bills through LabCorp | Patient TM • Engaging with consumers in new ways: • Automatic reminders, service confirmations, and call back texts when it is time to be serviced • Real-time capture of feedback including Net Promoter Scoring • Dedicated care team for consumers • Feedback loop with employees • Omni channel marketing and communication including social media • Relevant, valuable, personalized content 77


 
Seamless mobile experience to make reservations, automatically incorporating demographic and insurance information on file 78 LabCorp | PreCheck™


 
Streamlined experience for patient check-in with minimal manual entry 79 LabCorp | Express™


 
Patient Out-of-Pocket Cost Estimates • The estimator service is enabled across the LabCorp PSC network and for LabCorp in-office phlebotomists • Estimates are customized for each individual and health plan • For select genetic testing, consumers can obtain cost estimates online without visiting a PSC 80


 
Every patient that registers in LabCorp | Patient™ is given the opportunity to participate in research LabCorp | Patient™ All test results displayed in an easy to read and intuitive visual plus official report available for download 81


 
82 LabCorp at Walgreens LabCorp PSCs in Walgreens stores are attracting new patients 28% 18% 0% 10% 20% 30% LabCorp at Walgreens PSCs Comparable LabCorp PSCs % of patients seen new to LabCorp


 
83 Meeting Consumers Where They Want to be Met Consumer genetics Telemedicine Home health


 
Moving Reliable Self-Collected Testing to the Home 84 Illustrative


 
85 Key Takeaways Consumer engagement is vital to Diagnostics, Drug Development, and other key stakeholders (e.g., managed care, providers) Deploying industry-leading technology-enabled solutions will improve the consumer experience Our consumer platform will continue to accelerate revenue growth


 
Finance Overview Glenn Eisenberg Chief Financial Officer


 
87 The LabCorp Playbook: Delivering Long-Term Shareholder Value Revenue Growth Margin Optimization EPS Growth Disciplined Capital Deployment Return Capital to Shareholders Capital Expenditures and Strategic Acquisitions Capital Expenditures and LaunchPad Initiatives Strong Cash Flow


 
88 Track Record of Accelerating Growth $6.0 $6.2 $6.6 $6.9 $7.1 $0.0 $2.0 $4.0 $6.0 $8.0 $10.0 $12.0 $14.0 2014 2015 2016 2017 2018 $2.3 $6.80 $7.91 $8.83 $9.60 $0.00 $2.00 $4.00 $6.00 $8.00 $10.00 $12.00 $14.00 $16.00 2014 2015 2016 2017 2018 Revenue Adjusted EPS(3) $11.50 $9.4 $10.4 $11.5 (In Billions) $536 $727 $897 $1,147 $1,150 $0 $200 $400 $600 $800 $1,000 $1,200 $1,400 2014 2015 2016 2017 2018 (In Millions) Free Cash Flow(4) $8.5 2018 Guidance(1) Midpoint 10.5% (1) Guidance issued on February 6, 2017 (2) Includes the estimated impact from adoption of the new revenue recognition accounting standard (ASC 606). See Appendix for details of the preliminary reconciliation of 2017 results 2018 Guidance(1) Midpoint 19.8% 2018 Guidance(1) Midpoint $2.8 $3.6 (2) (2) $4.3 Drug Development Diagnostics (4) Free Cash Flow represents Operating Cash Flow less Capital Expenditures in each of the years presented. See Appendix for non-GAAP reconciliation (3) EPS, as presented, represents adjusted, non-GAAP financial measures (excludes amortization, restructuring and other special charges). See Appendix for non-GAAP reconciliation


 
89 2018 Guidance (1) Calculated based on the preliminary restatement of revenue in 2017 related to the Company’s adoption of the new revenue recognition accounting standard (ASC 606) effective January 1, 2018. See Appendix for additional details. Metric Guidance LabCorp Diagnostics Revenue Growth (1) 3.0% to 5.0% Covance Drug Development Revenue Growth (1) 20.0% to 24.0% Total Revenue Growth (1) 9.5% to 11.5% Tax Rate 25% Adjusted EPS $11.30 to $11.70 Free Cash Flow $1.1 to $1.2 Billion Capital Expenditures 3.5% of Revenue


 
90 2018 Adjusted EPS Guidance Bridge (1) (1) Adjusted EPS exclude amortization, restructuring charges and special items as well as a net benefit in the fourth quarter of 2017 of $5.00 per diluted share due to the implementation of the Tax Cuts and Jobs Act. See Appendix for non-GAAP reconciliation $7.00 $7.50 $8.00 $8.50 $9.00 $9.50 $10.00 $10.50 $11.00 $11.50 $12.00 2016 2017 Benefit from Lower Tax Rate Impact from PAMA Implementation Operating Performance 2018 $8.83 $9.60 $1.30 ($0.50) $11.30 - $11.70 $0.90 - $1.30 9% - 14% adjusted EPS growth in 2018 excluding the impact from the lower tax rate and implementation of PAMA


 
91 Disciplined Capital Deployment to Build Shareholder Value Approximately $11.5 Billion in Capital Deployment Between 2013 and 2017 49% 25% 15% 11% Covance Acquisition: $5.6 Billion Other Acquisitions: $2.9 Billion Share Repurchase: $1.7 Billion Capital Expenditures: $1.3 Billion


 
92 Targeted Capital Expenditures that Strengthen Capabilities and Support Growth ► Investments in 2018 to support future growth include: • Capacity and automation for 23andMe collaboration • Patient service centers in Walgreens stores • Genomics and immunotoxicology capabilities in drug development • Expanded capacity in Raritan, New Jersey regional laboratory, medical drug monitoring, and Shanghai drug development facilities ► Investment in LaunchPad initiatives, such as technology and automation 27% 46% 27% Capital Expenditures (2014 to 2018 Est.) Facilities IT Lab/Operations $0 $100 $200 $300 $400 2014 2015 2016 2017 2018 3.0% 3.0% 3.0% 3.4% 3.5% (2) (1) Percent calculated based on the preliminary restatement of revenue in 2017 related to the Company’s adoption of the new revenue recognition accounting standard (ASC 606) effective January 1, 2018. See Appendix for additional details. (2) Based on the midpoint of revenue guidance issued on February 6, 2017 Capital Expenditures by Year ($ in Millions; % of Revenue) (1)


 
93 Track Record of Acquisitions that Drive Growth and a Differentiated Offering Target Acquisition Criteria • Businesses that leverage our core competencies • Market leader • Strong management team • International presence • Accretive to earnings and cash flow year 1 • Earn cost of capital by year 3


 
0.0x 1.0x 2.0x 3.0x 4.0x $0 $200 $400 $600 $800 $1,000 $1,200 2013 2014 2015 2016 2017 94 Strong Balance Sheet Enables Return of Capital to Shareholders Debt and Leverage: • Investment grade philosophy with targeted leverage of 2.5x – 3.0x gross debt to EBITDA • Strong liquidity including $1 billion in unutilized revolving credit facility • Attractive debt profile – ~80% is fixed interest rate debt and ~75% of the debt matures in 2022 or later Share Repurchases: • Repurchased $1.7 billion over past five years • Existing authorization to buyback up to $407.4 million in shares • Expect to repurchase shares throughout 2018 0.0x 0.5x 1.0x 1.5x 2.0x 2.5x 3.0x 3.5x 4.0x $0 $200 $400 $600 $800 $1,000 $1,200 2013 2014 2015 2016 2017 Share Repurchases (In Millions) Leverage Leverage 0.0x 0.5x 1.0x 1.5x 2.0x 2.5x 3.0x 3.5x 4.0x $0 $200 $400 $600 $800 $1,000 $1,200 2013 2014 2015 2016 2017 Share Buyback 0.0x 0.5x 1.0x 1.5x 2.0x 2.5x 3.0x 3.5x 4.0x $0 $200 $400 $600 $800 $1,000 $1,200 2013 2014 2015 2016 2017 Covance Acquisition Date: Feb. 19, 2015 Leverage = 4.2x Chiltern Acquisition Date: Sept. 1, 2017 Leverage = 3.5x


 
95 Key Takeaways Multi-faceted platform for profitable growth through organic initiatives, strategic acquisitions, and margin optimization Track record of strong and reliable free cash flow, and disciplined capital deployment Execution of the LabCorp playbook continues to generate long-term shareholder value


 
Appendix


 
Reconciliation of Non-GAAP Financial Measures 97 Adjusted EPS 2014 2015 2016 2017 Diluted earnings per common share 5.91$ 4.35$ 7.02$ 12.21$ One-time benefit from Tax Cuts and Jobs Act - - - (5.00) Restructuring and special items 0.34 2.44 0.64 0.98 Amortization expense 0.55 1.12 1.17 1.41 Adjusted EPS 6.80$ 7.91$ 8.83$ 9.60$ Free Cash Flow: Net cash provided by operating activities 739$ 982$ 1,176$ 1,459$ Less: Capital expenditures (204) (256) (279) (313) Free cash flow 536$ 727$ 897$ 1,147$ (in millions, except per share data) Twelve Months Ended December 31,


 
98 Preliminary Reconciliation for the New Revenue Recognition Accounting Standard (ASC 606) Effective January 1, 2018, the Company adopted the FASB-issued converged standard on revenue recognition, using the full retrospective method. Although the Company has not completed all of the analysis required to finalize this restatement of revenues and expenses relating to this new standard, the table below presents the Company’s current best estimate of the potential financial impact on its two segments’ revenue, and is being provided as a reference point for the Company’s guidance in 2018. The 2017 calculation is preliminary and will be finalized upon adoption in the first quarter of 2018 and the amounts are therefore subject to change. The Company does not believe the application of the new standard will have any significant impact on previously reported Adjusted Operating Income. However, the change in reported revenue will impact previously reported operating margins as shown in the table provided. (1) In LabCorp Diagnostics, the impact of the accounting change will reduce revenue and increase margins, as bad debt will be treated as a reduction in revenue rather than selling, general and administrative expense (2) In Covance Drug Development, the impact of this accounting change will increase revenue and cost of revenue, resulting in lower margins due to the inclusion of investigator fees and other pass-through expenses in both categories (Dollars in millions) As Reported Preliminary Restatement LabCorp Diagnostics (1) Net Revenue 7,170.5$ 6,858.0$ Adjusted Operating Income 1,446.3$ 1,446.3$ Adjusted Operating Margin 20.2% 21.1% Covance Drug Development (2) Net Revenue 3,037.2$ 3,562.4$ Adjusted Operating Income 422.4$ 425.7$ Adjusted Operating Margin 13.9% 11.9% Consolidated (1) (2) Net Revenue 10,205.9$ 10,418.6$ Adjusted Segment Operating Income 1,868.7$ 1,872.0$ Unallocated corporate expense (137.4)$ (137.4)$ Consolidated Adjusted Operating Income 1,731.3$ 1,734.6$ Adjusted Operating Margin 17.0% 16.6% Twelve Months Ended December 31, 2017 Twelve Months Ended December 31, 2017


 
Lunch and Q&A